RNA Degradation	Splicing in Cancer	Intron and Ribosome Function	Directions	Français

Our group is interested in understanding the basic mechanism of RNA processing and degradation and its impact on the biology of cancer cells. RNA often functions as the channel through which information stored in genes is translated into cellular phenotypes. Modulation of RNA maturation or stability may alter the outcome of a single DNA sequence permitting a single gene to control many and in some cases opposing cellular functions. We use a multidisciplinary approach that combines genetics, biochemistry and cell biology to understand how RNA modify the blue print of eukaryotic cells to generate the functional specialization required for coping with the ever changing growth environment of living organisms.