RNA Degradation	Splicing in Cancer	Intron Function

 General research interest: three main axes.

RNA was believed to be an inert messenger or a scaffold that support protein function. However, recent study demonstrated that RNA is a versatile and active molecule that can possess enzymatic activity and modify the architecture of and function of any genome.

In our laboratory we are interested in understanding the mechanism that regulate RNA processing, stability and function. We study selective RNA degradation, splicing and ribosome biogenesis to determine how RNA synthesis and stability may shapes cell response to changes in growth conditions and tumor development.